Oxcarbazepine induced toxic epidermal necrolysis - a rare case report
نویسندگان
چکیده
منابع مشابه
Toxic epidermal necrolysis. A case report.
We present an extreme case of Toxic Epidermal Necrolysis, which corresponds to a severe form of Stevens Johnson Syndrome. This is a potentially fatal immune reaction that affects skin and mucosa, producing blisters and sloughing of the epithelium. Severe sequelae, including blindness, hearing loss, tooth malformation and esophageal destruction are seen in this case.
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We present a case of phenytoin-induced toxic epidermal necrolysis resulting in 60-70% skin involvement. Systemic corticosteroids and prophylactic antibiotics used initially were discontinued, and subsequent management concentrated on intensive supportive treatment. The patient survived, but is left with disabling ocular complications.
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Toxic epidermal necrolysis (TEN) is severe cutaneous hypersensitivity reaction characterized by necrosis of the epidermis and detachment of the epidermis and dermis that usually occurs as an idiosyncratic reaction to certain drugs. We report the case of a patient admitted to our Intensive Care Unit after an above-the-knee amputation who developed toxic epidermal necrolysis, possibly resulting f...
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Drug induced toxic epidermal necrolysis and Stevens Johnson syndrome are more commonly associated with medications such as sulfonamides, penicillin, anticonvulsants, oxicam non-steroidal anti-inflammatory drugs, allopurinol and corticosteroids. Isolated instances secondary to drugs outside of the aforementioned classes have also been reported. We report a case of probable toxic epidermal necrol...
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continued. Four to fi ve days later patient again developed generalised body rashes with greater intensity for which she was referred to us. On examination she was febrile, vitals were stable, had erythematous patches over both malar prominences with haemorrhagic crusts present over the lips and anterior nares (Fig. 1), multiple areas of erosions all over the body with thick adherent yellow cru...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmacology
سال: 2015
ISSN: 0253-7613
DOI: 10.4103/0253-7613.161279